Pub. Date : 2018 Dec 15
PMID : 30120973
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of CYP2R1 gene variants on vitamin D levels and status: A systematic review and meta-analysis. | Vitamin D | cytochrome P450 family 2 subfamily R member 1 | Homo sapiens |
| 2 | BACKGROUND AND OBJECTIVE: CYP2R1 is a key gene in the vitamin D metabolic pathway. | Vitamin D | cytochrome P450 family 2 subfamily R member 1 | Homo sapiens |
| 3 | It has been suggested that CYP2R1 gene variants in European populations are associated with concentrations of 25(OH)D, a biomarker of vitamin D levels and status in peripheral blood. | Vitamin D | cytochrome P450 family 2 subfamily R member 1 | Homo sapiens |
| 4 | The objective of this meta-analysis was to evaluate the association between CYP2R1 gene variants and 25(OH)D levels and vitamin D status. | Vitamin D | cytochrome P450 family 2 subfamily R member 1 | Homo sapiens |
| 5 | CONCLUSION: Published articles provide evidence supporting a major role for the rs10741657 polymorphism of the CYP2R1 gene in determining 25(OH)D levels and the presence of vitamin D deficiency. | Vitamin D | cytochrome P450 family 2 subfamily R member 1 | Homo sapiens |