Protein Name cytochrome P450 family 2 subfamily R member 1
Organism Homo sapiens
Gene ID 120227
Gene Symbol

CYP2R1

UniProt Q6VVX0 (CP2R1_HUMAN)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 162
Description

cytochrome P450 family 2 subfamily R member 1

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]

synonyms
  • vitamin D 25-hydroxylase
  • cytochrome P450 2R1
  • cytochrome P450, family 2, R1
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Properties