Title : In Vitro Drug-Drug Interaction Potential of Sulfoxide and/or Sulfone Metabolites of Albendazole, Triclabendazole , Aldicarb, Methiocarb, Montelukast and Ziprasidone.

Pub. Date : 2018

PMID : 30117405






1 Functional Relationships(s)
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1 CYP2C8 was inhibited by montelukast, montelukast sulfoxide, montelukast sulfone, tribendazole, triclabendazole sulfoxide, and triclabendazole sulfone with IC50 of 0.08 microM, 0.05 microM, 0.02 microM, 3.31 microM, 8.95 microM, and 1.05 microM, respectively. triclabendazole sulfoxide cytochrome P450 family 2 subfamily C member 8 Homo sapiens