Pub. Date : 2018 Aug
PMID : 30116396
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nobiletin protects PC12 cells from ERS-induced apoptosis in OGD/R injury via activation of the PI3K/AKT pathway. | nobiletin | AKT serine/threonine kinase 1 | Rattus norvegicus |
2 | Mechanistic detections showed that the neuron-favorable and ERS-repressing contributions of NOB were, in part, a result of the activation of the PI3K/AKT pathway, which was validated by a specific PI3K/AKT inhibitor (LY294002). | nobiletin | AKT serine/threonine kinase 1 | Rattus norvegicus |
3 | Mechanistic detections showed that the neuron-favorable and ERS-repressing contributions of NOB were, in part, a result of the activation of the PI3K/AKT pathway, which was validated by a specific PI3K/AKT inhibitor (LY294002). | nobiletin | AKT serine/threonine kinase 1 | Rattus norvegicus |