Title : Selective up-regulation of cannabinoid CB1 receptor coupling to Go-proteins in suicide victims with mood disorders.

Pub. Date : 2018 Nov

PMID : 30099006






2 Functional Relationships(s)
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1 CB1 receptor-stimulated [35S]GTPgammaS binding was significantly greater in the PFC of MD compared with matched controls (23%, p < 0.05). Sulfur-35 cannabinoid receptor 1 Homo sapiens
2 Analysis of [35S]GTPgammaS-labelled Galpha subunits allowed for the detection of upregulated CB1 receptor coupling to Galphao, but not to Galphai1, Galphai2, Galphai3, Galphaz subunits, in the PFC from AD-free MD suicides. Sulfur-35 cannabinoid receptor 1 Homo sapiens