| Protein Name | cannabinoid receptor 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1268 |
| Gene Symbol | CNR1 |
| UniProt | P21554 (CNR1_HUMAN), S5TLS4 (S5TLS4_HUMAN), V5KA96 (V5KA96_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
1053
Total Number of Articles : 1882 |
Description |
cannabinoid receptor 1 |
| Gene Summary |
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] |
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| Properties | |