Pub. Date : 2018
PMID : 30087576
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The present study was designed to evaluate a chip-based digital PCR (dPCR) system for assessing HER2 amplification from formalin-fixed paraffin-embedded breast carcinoma tissue and to compare this system with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). | Paraffin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
2 | Conclusion: These results demonstrate that chip-based dPCR is suitable for HER2 amplification detection in formalin-fixed paraffin-embedded samples in a clinical setting, providing the advantages of superior turnaround time, cost-effectiveness, and increased precision with absolute quantification compared with conventional tests such as FISH and IHC. | Paraffin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |