Title : Sulforaphane Alleviates Lipopolysaccharide-induced Spatial Learning and Memory Dysfunction in Mice: The Role of BDNF-mTOR Signaling Pathway.

Pub. Date : 2018 Sep 15

PMID : 30086367






1 Functional Relationships(s)
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1 Furthermore, we found that ANA-12 (a TrkB inhibitor) or rapamycin (a mTOR inhibitor) could block the beneficial effects of SFN on LPS-induced cognitive dysfunction, and that hippocampal levels of synaptic proteins, BDNF-TrkB and mTOR signaling pathways were also notably changed. sulforaphane neurotrophic tyrosine kinase, receptor, type 2 Mus musculus