| Protein Name | neurotrophic tyrosine kinase, receptor, type 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18212 |
| Gene Symbol | Ntrk2 |
| UniProt | P15209 (NTRK2_MOUSE), Q3UHE3 (Q3UHE3_MOUSE), A0A286YDA3 (A0A286YDA3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
355
Total Number of Articles : 545 |
Description |
neurotrophic tyrosine kinase, receptor, type 2 |
| Gene Summary |
Enables brain-derived neurotrophic factor binding activity and brain-derived neurotrophic factor receptor activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; modulation of chemical synaptic transmission; and nervous system development. Acts upstream of or within several processes, including neurogenesis; neuronal action potential propagation; and positive regulation of peptidyl-serine phosphorylation. Located in several cellular components, including early endosome; postsynaptic density; and terminal bouton. Is expressed in several structures, including alimentary system; future brain; genitourinary system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; autistic disorder; developmental and epileptic encephalopathy 58; heroin dependence; and morbid obesity. Orthologous to human NTRK2 (neurotrophic receptor tyrosine kinase 2). [provided by Alliance of Genome Resources, Jun 2025] |
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