Title : Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness.

Pub. Date : 2018 Oct

PMID : 30073804






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1 BACKGROUND: We have previously shown that the deletion of the superoxide scavenger, CuZn superoxide dismutase, in mice (Sod1-/- mice) results in increased oxidative stress and an accelerated loss of skeletal muscle mass and force that mirror the changes seen in old control mice. Superoxides superoxide dismutase 1, soluble Mus musculus