Title : The Role of Calcium in Inflammation-Associated Bone Resorption.

Pub. Date : 2018 Aug 1

PMID : 30071694






1 Functional Relationships(s)
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1 We used a burn injury setting in humans and a burn injury model in animals in order to examine the effects on the bone of the systemic inflammatory response and identified the parathyroid calcium-sensing receptor as the mediator of increasing bone resorption, hence higher interleukin (IL)-1 production, and decreasing bone resorption, hence the lowering of circulating ionized calcium concentration. Calcium interleukin 1 alpha Homo sapiens