Title : Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy.

Pub. Date : 2019 Jan

PMID : 30066239






3 Functional Relationships(s)
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1 Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy. goniothalamin ATP binding cassette subfamily B member 1 Homo sapiens
2 Among the goniothalamins, selective inhibitors of P-gp were discovered. goniothalamin ATP binding cassette subfamily B member 1 Homo sapiens
3 In conclusion, our findings revealed a novel role of goniothalamin derivatives in reversing P-gp-mediated chemotherapy resistance. goniothalamin ATP binding cassette subfamily B member 1 Homo sapiens