Title : Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives.

Pub. Date : 2018 Aug 15

PMID : 30057155






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Biological investigations showed that (+)-ursolic acid (1) is the major cytotoxic component of S. corticosum, which exhibited also potent activities in the NF-kappaB and mitochondrial transmembrane potential (MTP) inhibition assays conducted, with IC50 values of 31 nM and 3.5 microM, respectively. ursolic acid nuclear factor kappa B subunit 1 Homo sapiens