Title : CYP24A1 Inhibition Facilitates the Antiproliferative Effect of 1,25(OH)2D3 Through Downregulation of the WNT/β-Catenin Pathway and Methylation-Mediated Regulation of CYP24A1 in Colorectal Cancer Cells.

Pub. Date : 2018 Sep

PMID : 30052060






2 Functional Relationships(s)
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1 Furthermore, CYP24A1 mRNA expression in Caco2 cells was increased after demethylation treatment, and the expression of CYP24A1 induced by 1,25(OH)2D3 was significantly higher in cells treated with 5-aza-2"-deoxycytidine (DAC) than in an untreated group. Decitabine cytochrome P450 family 24 subfamily A member 1 Homo sapiens
2 Furthermore, CYP24A1 mRNA expression in Caco2 cells was increased after demethylation treatment, and the expression of CYP24A1 induced by 1,25(OH)2D3 was significantly higher in cells treated with 5-aza-2"-deoxycytidine (DAC) than in an untreated group. Decitabine cytochrome P450 family 24 subfamily A member 1 Homo sapiens