Protein Name cytochrome P450 family 24 subfamily A member 1
Organism Homo sapiens
Gene ID 1591
Gene Symbol


UniProt Q07973 (CP24A_HUMAN)
Relationships Total Number of functionally related compound(s) : 464
Total Number of Articles : 758

cytochrome P450 family 24 subfamily A member 1

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • 1,25-@dihydroxyvitamin D3 24-hydroxylase
  • 24-OHase
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