Title : Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.

Pub. Date : 2018 Jul 26

PMID : 30049282






1 Functional Relationships(s)
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1 Mutations identified in the radiation-associated DIPGs had significant molecular overlap with recurrent drivers of adult glioblastoma (e.g. NRAS, EGFR, and PTEN), as opposed to epigenetic dysregulation in H3-driven primary DIPGs. dipinacoline glutamate epidermal growth factor receptor Homo sapiens