Title : The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.

Pub. Date : 2018 Jul 20

PMID : 30037040






2 Functional Relationships(s)
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1 Among the pharmacological activities highlighted, anti-inflammatory activity was more evident than others, suggesting a multi-target Michael acceptor mechanism for the chalcones involving key regulators of the Nrf2 and nuclear factor- kappaB (NF-kappaB) pathways. Chalcones nuclear factor kappa B subunit 1 Homo sapiens
2 Among the pharmacological activities highlighted, anti-inflammatory activity was more evident than others, suggesting a multi-target Michael acceptor mechanism for the chalcones involving key regulators of the Nrf2 and nuclear factor- kappaB (NF-kappaB) pathways. Chalcones nuclear factor kappa B subunit 1 Homo sapiens