Title : The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.

Pub. Date : 2018 Sep

PMID : 30035852






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Depending on cell demands, serine hydroxymethyltransferase (SHMT) dynamically changes the fluxes of OCM by reversibly converting serine and tetrahydrofolate (THF) into 5,10-methylene-THF and glycine. Serine serine hydroxymethyltransferase 1 Homo sapiens