Pub. Date : 2018
PMID : 30029732
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DHEA is a product of the P450c17 (17alpha-hydroxylase-17,20-lyase) enzyme. | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | The depot of DHEA-SO4 that remains after P450c17 inhibition and the adaptive responses that occur within the tumor to promote DHEA utilization contribute to mechanisms of drug resistance observed with P450c17 inhibitors. | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 3 | The depot of DHEA-SO4 that remains after P450c17 inhibition and the adaptive responses that occur within the tumor to promote DHEA utilization contribute to mechanisms of drug resistance observed with P450c17 inhibitors. | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 4 | The depot of DHEA-SO4 that remains after P450c17 inhibition and the adaptive responses that occur within the tumor to promote DHEA utilization contribute to mechanisms of drug resistance observed with P450c17 inhibitors. | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |