Title : Rational engineering of ornithine decarboxylase with greater selectivity for ornithine over lysine through protein network analysis.

Pub. Date : 2018 Sep 10

PMID : 30021117






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Ornithine decarboxylase (ODC) converts C5 ornithine into C4 putrescine, a monomer for polyamide synthesis. Ornithine ornithine decarboxylase 1 Homo sapiens
2 Ornithine decarboxylase (ODC) converts C5 ornithine into C4 putrescine, a monomer for polyamide synthesis. Ornithine ornithine decarboxylase 1 Homo sapiens
3 Here, to increase ODC substrate specificity toward ornithine over lysine, molecular modelling and protein network analysis, specifically k-clique community analysis, around the substrate tunnel were performed. Ornithine ornithine decarboxylase 1 Homo sapiens