Title : Structural Divergence in O-GlcNAc Glycans Displayed on Epidermal Growth Factor-like Repeats of Mammalian Notch1.

Pub. Date : 2018 Jul 17

PMID : 30018219






2 Functional Relationships(s)
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1 Although the majority of Notch1 EGF2 and EGF20 domains contained the extended forms of the glycan, the O-GlcNAc in many other domains mostly existed as a monosaccharide irrespective of the exogenous EOGT expression. Monosaccharides O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
2 Our results raised a hypothesis that an array of O-GlcNAc monosaccharides may impact the structure and function of Notch receptors. Monosaccharides O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens