Pub. Date : 2018 Sep
PMID : 30015875
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, when combined with 2-deoxyglucose (2-DG), the anticancer effect of the Bcl-2 inhibitor ABT737 was greatly potentiated and hypoxia-inducible factor 1alpha (HIF-1alpha) appeared to be closely associated with Bcl-2 family members in the regulation of glucose metabolism. | Glucose | BCL2 apoptosis regulator | Homo sapiens |
2 | Furthermore, when combined with 2-deoxyglucose (2-DG), the anticancer effect of the Bcl-2 inhibitor ABT737 was greatly potentiated and hypoxia-inducible factor 1alpha (HIF-1alpha) appeared to be closely associated with Bcl-2 family members in the regulation of glucose metabolism. | Glucose | BCL2 apoptosis regulator | Homo sapiens |
3 | These results suggested that the special glucose metabolism in SKOV3/DDP cells might be selectively targeted by disrupting Bcl-2-dependent OXPHOS. | Glucose | BCL2 apoptosis regulator | Homo sapiens |