Pub. Date : 2018 Aug 20
PMID : 29966698
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cerebroprotection by salvianolic acid B after experimental subarachnoid hemorrhage occurs via Nrf2- and SIRT1-dependent pathways. | salvianolic acid B | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |
| 2 | Moreover, SalB dramatically induced nuclear factor-erythroid 2-related factor 2 (Nrf2) nuclear translocation and increased expression of heme oxygenase-1 and NADPH: quinine oxidoreductase-1. | salvianolic acid B | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |
| 3 | Taken together, these in vivo and in vitro findings suggest that SalB provides protection against SAH-triggered oxidative damage by upregulating the Nrf2 antioxidant signaling pathway, which may be modulated by SIRT1 activation. | salvianolic acid B | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |