Pub. Date : 2018 Jul
PMID : 29962852
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In RAW264.7 cells stimulated with LPS, adenine inhibited production of pro-inflammatory cytokines TNF-alpha and IL-6 and inflammatory lipid mediators, prostaglandin E2 and leukotriene B4. | Adenine | interleukin 6 | Mus musculus |
| 2 | In BMMCs, adenine inhibited the LPS-induced production of TNF-alpha, IL-6 and IL-13 and also hindered phosphorylation of NF-kappaB and Akt. | Adenine | interleukin 6 | Mus musculus |
| 3 | In peritoneal cavity, adenine suppressed the LPS-induced production of TNF-alpha and IL-6 by peritoneal cells in mice. | Adenine | interleukin 6 | Mus musculus |