Title : BET Inhibition Suppresses S100A8 and S100A9 Expression in Acute Myeloid Leukemia Cells and Synergises with Daunorubicin in Causing Cell Death.

Pub. Date : 2018

PMID : 29955397






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Daunorubicin alone causes a dose- and time-dependent increase in S100A8 and S100A9 protein levels in AML cell lines which is overcome by cotreatment with JQ1. Daunorubicin S100 calcium binding protein A8 Homo sapiens
2 This suggests that JQ1 synergises with daunorubicin in causing apoptosis via suppression of S100A8 and S100A9 levels. Daunorubicin S100 calcium binding protein A8 Homo sapiens