Protein Name | S100 calcium binding protein A8 |
---|---|
Organism | Homo sapiens |
Gene ID | 6279 |
Gene Symbol | S100A8 |
UniProt | P05109 (S10A8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
340
Total Number of Articles : 502 |
Description |
S100 calcium binding protein A8 |
Gene Summary |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
synonyms |
|
Properties | |