Protein Name S100 calcium binding protein A8
Organism Homo sapiens
Gene ID 6279
Gene Symbol

S100A8

UniProt P05109 (S10A8_HUMAN)
Relationships Total Number of functionally related compound(s) : 340
Total Number of Articles : 502
Description

S100 calcium binding protein A8

Gene Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

synonyms
  • protein S100-A8
  • calgranulin A
  • calprotectin L1L subunit
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Properties