Title : Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib.

Pub. Date : 2018 Oct

PMID : 29932973






1 Functional Relationships(s)
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1 All of that provided possibility to overcome the intolerance of sorafenib by drug compatibility through protection against mitochondria damage, inhibition of anaerobic glycolysis and suppression of lipid synthesis based on PI3K/Akt/mTOR pathway. Sorafenib mechanistic target of rapamycin kinase Mus musculus