Title : Proteomic determination of the lysine acetylome and phosphoproteome in the rat native inner medullary collecting duct.

Pub. Date : 2018 Sep 1

PMID : 29932826






4 Functional Relationships(s)
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1 We recently reported that the inner medullary collecting duct (IMCD), which functions in the regulation of water-reabsorption, via the actions of vasopressin, expresses many of the enzymes that can modulated K-acetylation. Water arginine vasopressin Rattus norvegicus
2 The acetylated proteins were expressed in all compartments of the cell and were enriched in pathways including glycolysis and vasopressin-regulated water reabsorption. Water arginine vasopressin Rattus norvegicus
3 In the vasopressin-regulated water reabsorption pathway, eight proteins were acetylated, including the novel identification of the basolateral water channel, AQP3, acetylated at K282; 215 proteins were phosphorylated in this IMCD cohort, including AQP2 peptides that were phosphorylated at four serines: 256, 261, 264, and 269. Water arginine vasopressin Rattus norvegicus
4 In the vasopressin-regulated water reabsorption pathway, eight proteins were acetylated, including the novel identification of the basolateral water channel, AQP3, acetylated at K282; 215 proteins were phosphorylated in this IMCD cohort, including AQP2 peptides that were phosphorylated at four serines: 256, 261, 264, and 269. Water arginine vasopressin Rattus norvegicus