Title : Gangliosides and Tumors.

Pub. Date : 2018

PMID : 29926407






1 Functional Relationships(s)
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1 Tumor-associated gangliosides play important roles in regulation of signal transduction induced by growth-factor receptors including EGFR, FGFR, HGF and PDGFR in a specific microdomain called glycosynapse in the cancer cell membranes, and in interaction with glycan recognition molecules involved in cell adhesion and immune regulation including selectins and siglecs. Gangliosides epidermal growth factor receptor Homo sapiens