Pub. Date : 1985 Jul 15
PMID : 2989289
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Studies utilizing the inactivation of myeloperoxidase by hydrogen peroxide and azide. | Azides | myeloperoxidase | Homo sapiens |
| 2 | In this report, we show that myeloperoxidase is also inactivated by H2O2 plus azide. | Azides | myeloperoxidase | Homo sapiens |
| 3 | Stimulation of neutrophils with phorbol myristate acetate (PMA, 100 ng/ml) plus azide (5 mM) for 30 min completely inactivated intragranular myeloperoxidase and reduced cytosolic catalase to 35% of resting cells. | Azides | myeloperoxidase | Homo sapiens |
| 4 | Incubation of neutrophils with azide and a H2O2 generating system (glucose-glucose oxidase) inactivated 41% of neutrophil myeloperoxidase. | Azides | myeloperoxidase | Homo sapiens |
| 5 | Glutathione-glutathione peroxidase (GSH-GSH peroxidase), an extracellular H2O2 scavenger, totally protected neutrophil myeloperoxidase from inactivation by azide plus glucose-glucose oxidase. | Azides | myeloperoxidase | Homo sapiens |
| 6 | In addition, when a mixture of normal and CGD cells was stimulated with PMA in the presence of azide, 90% of the myeloperoxidase in CGD neutrophils was inactivated. | Azides | myeloperoxidase | Homo sapiens |
| 7 | In contrast, myeloperoxidase in normal polymorphonuclear leukocytes stimulated with PMA in the presence of azide and GSH-GSH peroxidase was 75% inactivated. | Azides | myeloperoxidase | Homo sapiens |