Title : Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma.

Pub. Date : 2018 Jun 11

PMID : 29891006






2 Functional Relationships(s)
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1 BACKGROUND: SOD1 is an abundant enzyme that has been studied as a regulator of the antioxidant defence system, and this enzyme is well known for catalyzing the dismutation of superoxide into hydrogen peroxide. Superoxides superoxide dismutase 1, soluble Mus musculus
2 We demonstrated that these mechanisms of SOD1 partly exist to maintain low levels of the superoxide anion and to avoid the accumulation of lipid droplets via enhanced CPT1A-mediated fatty acid oxidation. Superoxides superoxide dismutase 1, soluble Mus musculus