Pub. Date : 2018 Sep
PMID : 29886067
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bexarotene protects against neurotoxicity partially through a PPARgamma-dependent mechanism in mice following traumatic brain injury. | Bexarotene | peroxisome proliferator activated receptor gamma | Mus musculus |
| 2 | These effects of bexarotene were partially abolished by T0070907, an antagonist of peroxisome proliferator-activated receptor gamma (PPARgamma). | Bexarotene | peroxisome proliferator activated receptor gamma | Mus musculus |
| 3 | These effects of bexarotene were partially abolished by T0070907, an antagonist of peroxisome proliferator-activated receptor gamma (PPARgamma). | Bexarotene | peroxisome proliferator activated receptor gamma | Mus musculus |
| 4 | Additionally, bexarotene enhanced nuclear translocation and transcriptional activity of PPARgamma. | Bexarotene | peroxisome proliferator activated receptor gamma | Mus musculus |
| 5 | These findings show that bexarotene inhibits neurotoxicity in mice after TBI, at least in part through a PPARgamma-dependent mechanism. | Bexarotene | peroxisome proliferator activated receptor gamma | Mus musculus |