Title : Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERĪ± Signaling.

Pub. Date : 2018

PMID : 29867480






1 Functional Relationships(s)
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1 Furthermore, our studies showed that icariin exerted stronger anti-apoptotic effects than genistein and 17beta-estradiol (E2) and inhibited the cleavage of downstream caspase-3 in MC3T3-E1 cells induced by a potent PI3K inhibitor, PI828 (at 2 muM). icariin caspase 3 Mus musculus