Title : SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand.

Pub. Date : 2018 May 18

PMID : 29861877






1 Functional Relationships(s)
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1 Contrasting results, however, have been reported on the capability of variants of other genes as MTHFR, TYMS, ERCC1, XRCC1, GSTP1, CYP3A4/3A5 and ABCB1, in predicting either therapy efficacy or toxicity in patients undergoing treatment with pyrimidine antimetabolites, platinum derivatives, irinotecan and taxanes. Irinotecan thymidylate synthetase Homo sapiens