Title : (S)-crizotinib reduces gastric cancer growth through oxidative DNA damage and triggers pro-survival akt signal.

Pub. Date : 2018 May 31

PMID : 29855474






1 Functional Relationships(s)
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1 Results indicated that (S)-crizotinib decreased GC cell viability, induced growth arrest and apoptosis, and increased levels of gammaH2AX and Ser1981-phosphorylated ATM, which were inhibited by NAC. Crizotinib NLR family, pyrin domain containing 1A Mus musculus