Title : Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair.

Pub. Date : 2018 Jul

PMID : 29844578






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Upon DNA damage, H1.2 undergoes rapid PARP1-dependent chromatin dissociation through poly-ADP-ribosylation (PARylation) of its C terminus and further proteasomal degradation. poly-adp poly(ADP-ribose) polymerase 1 Homo sapiens