Title : Persistent 3'-phosphate termini and increased cytotoxicity of radiomimetic DNA double-strand breaks in cells lacking polynucleotide kinase/phosphatase despite presence of an alternative 3'-phosphatase.

Pub. Date : 2018 Aug

PMID : 29807321






1 Functional Relationships(s)
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1 Moreover, NCS-induced DSBs, detected as 53BP1 foci, were more persistent in PNKP -/- HCT116 cells compared to their wild-type (WT) counterparts. dsbs tumor protein p53 binding protein 1 Homo sapiens