Pub. Date : 2018 Jun
PMID : 29805654
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cisplatin-induced non-canonical endocytosis of EGFR via p38 phosphorylation of the C-terminal region containing Ser-1015 in non-small cell lung cancer cells. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 2 | In the present study, the role of non-canonical EGFR regulation has been investigated in NSCLC cells treated with cisplatin, a common chemotherapeutic agent. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 3 | Cisplatin-induced p38 activation triggered the Ser-1015 phosphorylation of EGFR, with similar kinetics to previously reported Ser-1047 phosphorylation, in a tyrosine kinase-independent manner. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 4 | The results of the present study provide mechanistic evidence for the cisplatin-induced non-canonical regulation of EGFR. | Cisplatin | epidermal growth factor receptor | Homo sapiens |