Title : α-Lipoic acid inhibits the migration and invasion of breast cancer cells through inhibition of TGFβ signaling.

Pub. Date : 2018 Aug 15

PMID : 29802942






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The inhibition of cell migration by lipoic acid is accompanied by the downregulation of FAK, ERK1/2 and AKT phosphorylation, and inhibition of nuclear translocation of beta-catenin. Thioctic Acid AKT serine/threonine kinase 1 Homo sapiens
2 SIGNIFICANCE: Our data demonstrated that lipoic acid inhibited the migration and invasion of metastatic breast cancer cells at least in part through inhibiting ERK1/2 and AKT signaling. Thioctic Acid AKT serine/threonine kinase 1 Homo sapiens