Title : Bafilomycin C1 induces G0/G1 cell-cycle arrest and mitochondrial-mediated apoptosis in human hepatocellular cancer SMMC7721 cells.

Pub. Date : 2018 Sep

PMID : 29752478






1 Functional Relationships(s)
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1 Western blot and real-time qPCR analysis revealed that bafilomycin C1 caused partial G0/G1 phase cell-cycle arrest, downregulated the expression of cyclin D3, cyclin E1, CDK2, CDK4, and CDK6 and upregulated the expression of p21. bafilomycin C1 cyclin dependent kinase 2 Homo sapiens