Pub. Date : 2018 Jul
PMID : 29752413
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation. | Everolimus | calcineurin binding protein 1 | Homo sapiens |
2 | Background Everolimus permits reduced calcineurin inhibitor (CNI) exposure, but the efficacy and safety outcomes of this treatment after kidney transplant require confirmation.Methods In a multicenter noninferiority trial, we randomized 2037 de novo kidney transplant recipients to receive, in combination with induction therapy and corticosteroids, everolimus with reduced-exposure CNI (everolimus arm) or mycophenolic acid (MPA) with standard-exposure CNI (MPA arm). | Everolimus | calcineurin binding protein 1 | Homo sapiens |