Title : Increase in tacrolimus exposure after steroid tapering is influenced by CYP3A5 and pregnane X receptor genetic polymorphisms in renal transplant recipients.

Pub. Date : 2018 Sep 1

PMID : 29733390






2 Functional Relationships(s)
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1 Background: Tacrolimus, a drug for prevention of rejection after kidney transplantation, has a narrow therapeutic window and is metabolized by the cytochrome P540 3A (CYP3A) system. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Background: Tacrolimus, a drug for prevention of rejection after kidney transplantation, has a narrow therapeutic window and is metabolized by the cytochrome P540 3A (CYP3A) system. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens