Pub. Date : 2018 May
PMID : 29731858
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, the role of peroxisome proliferator-activated receptor gamma (PPARgamma) in the effect of lycopene and beta-carotene on the viability of EC109 human esophageal squamous carcinoma cells was investigated. | Lycopene | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 2 | In the present study, the role of peroxisome proliferator-activated receptor gamma (PPARgamma) in the effect of lycopene and beta-carotene on the viability of EC109 human esophageal squamous carcinoma cells was investigated. | Lycopene | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 3 | Lycopene and beta-carotene treatments upregulated the expression of PPARgamma and p21WAF1/CIP1, and downregulated the expression of cyclin D1 and COX-2. | Lycopene | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 4 | These modulatory effects of the carotenoid treatments were suppressed by GW9662, suggesting that the inhibition of EC109 cell viability by lycopene and beta-carotene involves PPARgamma signaling pathways and the modulation of p21WAF1/CIP1, cyclin D1 and COX-2 expression. | Lycopene | peroxisome proliferator activated receptor gamma | Homo sapiens |