Title : Decreased levels of keratin 8 sensitize mice to streptozotocin-induced diabetes.

Pub. Date : 2018 Oct

PMID : 29719117






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 K8 and its partner K18 are the main beta-cell keratins, and knockout of K8 (K8-/- ) in mice causes mislocalization of glucose transporter 2, mitochondrial defects, reduced insulin content and altered systemic glucose/insulin control. Glucose keratin 18 Mus musculus
2 K8 and its partner K18 are the main beta-cell keratins, and knockout of K8 (K8-/- ) in mice causes mislocalization of glucose transporter 2, mitochondrial defects, reduced insulin content and altered systemic glucose/insulin control. Glucose keratin 18 Mus musculus