Protein Name keratin 18
Organism Mus musculus
Gene ID 16668
Gene Symbol

Krt18

UniProt P05784 (K1C18_MOUSE)
Relationships Total Number of functionally related compound(s) : 64
Total Number of Articles : 61
Description

keratin 18

Gene Summary

Predicted to enable scaffold protein binding activity. Acts upstream of or within extrinsic apoptotic signaling pathway; hepatocyte apoptotic process; and tumor necrosis factor-mediated signaling pathway. Located in cell periphery and keratin filament. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT18 (keratin 18). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • keratin, type I cytoskeletal 18
  • cytokeratin endo B
  • cytokeratin-18
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Properties