Title : [Effect of Caveolae/Caveolin-1on Osteogenic Differentiation of Mesenchymal Stem Cells].

Pub. Date : 2016 Aug

PMID : 29714927






3 Functional Relationships(s)
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1 Mesenchymal stem cells(MSCs)have the property of osteogenic induction.As a result,using the property of MSCs to treat the fractures and bone defects has become a new treatment modality with the development of cell and tissue engineering technology.Caveolae is a flask-shaped membrane microdomain in cell membrane,which composed primarily of cholesterol,sphingolipids and proteins.Caveolin-1is one of the main protein component.Caveolae is the integrator of cell signals,and many signal molecules gather here to bind with caveolin-1protein to regulate cell proliferation,differentiation and other life activities.This paper presents a review about Caveolae/Caveolin-1biologic effects on cell differentiation of MSCs. Cholesterol caveolin 1 Homo sapiens
2 Mesenchymal stem cells(MSCs)have the property of osteogenic induction.As a result,using the property of MSCs to treat the fractures and bone defects has become a new treatment modality with the development of cell and tissue engineering technology.Caveolae is a flask-shaped membrane microdomain in cell membrane,which composed primarily of cholesterol,sphingolipids and proteins.Caveolin-1is one of the main protein component.Caveolae is the integrator of cell signals,and many signal molecules gather here to bind with caveolin-1protein to regulate cell proliferation,differentiation and other life activities.This paper presents a review about Caveolae/Caveolin-1biologic effects on cell differentiation of MSCs. Cholesterol caveolin 1 Homo sapiens
3 Mesenchymal stem cells(MSCs)have the property of osteogenic induction.As a result,using the property of MSCs to treat the fractures and bone defects has become a new treatment modality with the development of cell and tissue engineering technology.Caveolae is a flask-shaped membrane microdomain in cell membrane,which composed primarily of cholesterol,sphingolipids and proteins.Caveolin-1is one of the main protein component.Caveolae is the integrator of cell signals,and many signal molecules gather here to bind with caveolin-1protein to regulate cell proliferation,differentiation and other life activities.This paper presents a review about Caveolae/Caveolin-1biologic effects on cell differentiation of MSCs. Cholesterol caveolin 1 Homo sapiens