Pub. Date : 2018 Apr 27
PMID : 29703933
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we report that the cysteine-reactive molecule ebselen efficiently confers the SOD1 intra-subunit disulphide and directs correct SOD1 folding, depopulating the globally unfolded precursor associated with aggregation and toxicity. | disulphide | superoxide dismutase 1 | Homo sapiens |
| 2 | Assisted formation of the unusual SOD1 cytosolic disulphide bond could have potential therapeutic applications. | disulphide | superoxide dismutase 1 | Homo sapiens |