Title : Curcumin reverses diabetes-induced endothelial progenitor cell dysfunction by enhancing MnSOD expression and activity in vitro and in vivo.

Pub. Date : 2018 Jul

PMID : 29702753






8 Functional Relationships(s)
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1 Curcumin reverses diabetes-induced endothelial progenitor cell dysfunction by enhancing MnSOD expression and activity in vitro and in vivo. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
2 The levels and activity of manganese superoxide dismutase (MnSOD) in D-EPCs treated in vitro with curcumin or those isolated from curcumin-treated diabetic mice were comparable with those in non-diabetic EPCs. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
3 The levels and activity of manganese superoxide dismutase (MnSOD) in D-EPCs treated in vitro with curcumin or those isolated from curcumin-treated diabetic mice were comparable with those in non-diabetic EPCs. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
4 The levels and activity of manganese superoxide dismutase (MnSOD) in D-EPCs treated in vitro with curcumin or those isolated from curcumin-treated diabetic mice were comparable with those in non-diabetic EPCs. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
5 The levels and activity of manganese superoxide dismutase (MnSOD) in D-EPCs treated in vitro with curcumin or those isolated from curcumin-treated diabetic mice were comparable with those in non-diabetic EPCs. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
6 Addition of methyl mercury chloride to inhibit MnSOD activity during curcumin treatment abolished the salutary effects of curcumin. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
7 Addition of methyl mercury chloride to inhibit MnSOD activity during curcumin treatment abolished the salutary effects of curcumin. Curcumin superoxide dismutase 2, mitochondrial Mus musculus
8 Our data demonstrate that curcumin reverses DM-induced EPCD by boosting MnSOD expression and activity and emphasizes its potential for use in autologous cell therapy for diabetic wound management. Curcumin superoxide dismutase 2, mitochondrial Mus musculus