Title : Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity.

Pub. Date : 2018 Apr 25

PMID : 29695239






1 Functional Relationships(s)
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1 Resistance was shown to be mediated by down-regulation of the deoxycytidine kinase (dCK) protein, responsible for activation of nucleoside analogue prodrugs. Nucleosides Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster