Title : Structure-Activity Relationships of the Main Bioactive Constituents of Euodia rutaecarpa on Aryl Hydrocarbon Receptor Activation and Associated Bile Acid Homeostasis.

Pub. Date : 2018 Jul

PMID : 29691238






1 Functional Relationships(s)
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1 These findings revealed that the methyl group at the N-14 atom of these analogs and their pharmacokinetic behaviors were the main determinants for AHR activation, and suggest that attention should be given to monitoring bile acid metabolism in the clinical use of E. rutaecarpa. Nitrogen aryl-hydrocarbon receptor Mus musculus